Emperor of the Fading Suns

Intriguing Civ style game from the EotFS paper RPG Universe.

Up to 5 players take the role of Houses vying for control of the known galaxy by winning political votes and siezing power.

One of many interesting game mechanics is some technolgies are "banned" by the church, and players who research it may be punished for forbidden knowledge if/when the church finds out!